The Swiss National Center of Competence in Research (NCCR) Structural Biology is a research consortium specializing in the structural biology of membrane proteins and supramolecular complexes. It is funded by the Swiss Science Foundation (SNF), the University of Zürich (UZH), and the ETH Zürich (ETH). Its network includes 14 research groups at the UZH, ETH, the Paul Scherrer Institute (PSI), the Swiss Light Source (SLS),
and the Biozentrum of the University of Basel. 

In focus

Cryo-EM Structures of Arx1 and Maturation Factors Rei1 and Jjj1 Bound to the 60S Ribosomal Subunit

12.11.2012. Structural insights into eukaryotic ribosome biogenesis.


Barandun J, Delley CL, Weber-Ban E. (2012) The pupylation pathway and its role in mycobacteria. BMC Biol. Nov 30;10:95. doi: 10.1186/1741-7007-10-95. PubMed

Zimmermann I, Marabelli A, Bertozzi C, Sivilotti LG, Dutzler R. (2012) Inhibition of the Prokaryotic Pentameric Ligand-Gated Ion Channel ELIC by Divalent Cations. PLoS Biol. Nov;10(11):e1001429. doi: 10.1371/journal.pbio.1001429. Epub 2012 Nov 20. PubMed

Scott DJ, Plückthun A. (2012) Direct Molecular Evolution of Detergent-Stable G Protein-Coupled Receptors using Polymer Encapsulated Cells. J Mol Biol. Nov 16. doi:pii: S0022-2836(12)00887-X. 10.1016/j.jmb.2012.11.015. [Epub ahead of print] PubMed

Borgia A, Wensley BG, Soranno A, Nettels D, Borgia MB, Hoffmann A, Pfeil SH, Lipman EA, Clarke J, Schuler B. (2012) Localizing internal friction along the reaction coordinate of protein folding by combining ensemble and single-molecule fluorescence spectroscopy. Nat Commun. Nov 13;3:1195. doi: 10.1038/ncomms2204. PubMed


A novel crystallization plate

The group of Markus Grütter at the University of Zurich developed a novel capillary crystallization plate - the CrystalHarp. Users of the NCCR Crystallization Facility interested in testing this plate may contact Beat Blattmann (email) or Mareike Kurz (email) for further information.

Picture Gallery

Impressions of the event
(Photos courtesy A. Honegger)

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